BREZTRI may help protect your lungs against COPD flare-ups.

BREZTRI can*:

GIVE YOUBETTERBREATHING.

IMPROVEYOUR COPDSYMPTOMS.

PROTECTAGAINST FUTUREFLARE-UPS.

*Results may vary

In fact, it’s the first and only COPD medicine proven to reduce COPD flare-ups by

Fifty Two Percent
Fifty Two Percent

†In a lung function study in patients with moderate to very severe COPD, with a majority having no flare-ups in the last 12 months. Flare-ups were reduced by 52% vs a dual bronchodilator—the combination of two medicines, an anticholinergic known as a long-acting muscarinic antagonist (LAMA) and a long-acting beta2-adrenergic agonist (LABA).

You could be eligible to get BREZTRI for as little as $0‡ with BREZTRI Zero Pay! Click here to find out more.

‡For eligible commercially insured patients only. Subject to applicable insurance plan’s eligibility rules and requirements; restrictions may apply.

COPD May Cause Permanent Lung Damage

You probably already know COPD can make it hard to breathe. But did you know those bad days you have—like needing to take oral steroids or seeking emergency care because of your COPD symptoms—could mean you’ve experienced a COPD flare-up (sometimes called an exacerbation). This is important to recognize because, in the real world, those COPD flare-ups may be causing permanent damage to your lungs.

About COPD and Flare-Ups

Get Real Protection Against COPD Flare-Ups with BREZTRI

See What BREZTRI Could Do for You

Talk to Your Doctor
About Real Protection

It’s never too early or too late to protect your breathing. Getting tips to help describe your COPD symptoms can help you start the conversation with your doctor and get an appropriate medication to help you§ breathe better, improve your COPD symptoms, and get real protection against COPD flare-ups. The BREZTRI Conversation Starter may help.

§Results may vary

Prepare for Your Appointment

§Results may vary

COPD Flare-Ups May Cause Permanent Lung Damage

Understanding what COPD and flare-ups are may help you manage your COPD. That’s important, because even if you’ve gotten used to them, those bad days you have (like having frequent respiratory infections or needing emergency care for your COPD symptoms) could mean you’ve experienced a COPD flare-up—and those could permanently damage your lungs.

About COPD and Flare-Ups

Start the Conversation About COPD Flare-Ups

Learning how to talk to your doctor about COPD flare-ups may help you and your doctor manage your COPD.

BREZTRI Conversation Starter

In the Real World, Your Lungs Deserve the Real Protection of BREZTRI

Get COPD Resources for You and Your Doctor

The BREZTRI Support Experience is full of information that is designed to help you and your doctor manage your COPD. The experience continues with access to educational resources, BREZTRI Zero Pay information, and instructions for using your inhaler.

Savings & Support
Find a Doctor Today
Breztri Zero Pay Card
Breztri Zero Pay Card

Frequently Asked Questions

What is the approved use for BREZTRI?

BREZTRI is a prescription medicine used long term to treat chronic obstructive pulmonary disease (COPD). COPD is a chronic lung disease...

What are COPD flare-ups?

A COPD flare-up—also known as an exacerbation—is a sudden worsening of your COPD symptoms that results in additional treatment. If your...

Are there savings offers for BREZTRI?

Yes. You may be eligible to pay as little as $0* on your prescription for BREZTRI for up to one year with BREZTRI Zero Pay. To find out if you qualify for...

How do I store my BREZTRI inhaler?

Store BREZTRI at room temperature between 68°F and 77°F (20°C and 25°C). Keep in a dry place away from heat and sunlight. Store BREZTRI in...

Get More Answers Here

BREZTRI is not a rescue inhaler and is not for asthma.

See the BREZTRI Prescribing Information here

Stay up-to-date with BREZTRI, get COPD tips, and more.

APPROVED USE

BREZTRI AEROSPHERE is a medicine used long term to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups.

BREZTRI is not used to relieve sudden breathing problems and will not replace a rescue inhaler. BREZTRI is not for the treatment of asthma.

Read More

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IMPORTANT SAFETY INFORMATION

  • BREZTRI combines 3 medicines, an inhaled corticosteroid (ICS) medicine (budesonide), an anticholinergic medicine (glycopyrrolate), and a long-acting beta2-adrenergic agonist (LABA) medicine (formoterol fumarate). LABA medicines, such as formoterol fumarate, when used alone can increase the risk of hospitalizations and death from asthma problems. When an ICS and LABA are used together, this risk is not significantly increased
  • Do not use BREZTRI if you are allergic to budesonide, glycopyrrolate, formoterol fumarate, or any of the ingredients in BREZTRI
  • Do not take BREZTRI with other medicines that contain a long-acting beta2-adrenergic agonist (LABA) or an anticholinergic for any reason. Tell your healthcare provider about all your medical conditions and about all the medicines you take
  • BREZTRI should be taken as 2 puffs, 2 times each day. Do not use BREZTRI more often than prescribed
  • Call your healthcare provider or get medical care right away if your breathing problems get worse, if you need to use your rescue inhaler more often than usual, or your rescue inhaler does not work as well to relieve your symptoms
  • BREZTRI can cause serious side effects, including:
    • Fungal infection in your mouth or throat (thrush). Rinse your mouth with water without swallowing after using BREZTRI to help reduce your chance of getting thrush
    • Pneumonia. People with COPD have a higher chance of getting pneumonia. Call your healthcare provider if you notice an increase in mucus (sputum) production or change in mucus color, fever, chills, increased cough, or increased breathing problems
    • Weakened immune system and increased chance of getting infections (immunosuppression)
    • Reduced adrenal function (adrenal insufficiency). This can happen when you stop taking oral corticosteroid medicines and start inhaled corticosteroid medicine
    • Sudden breathing problems immediately after inhaling BREZTRI. If this happens, stop taking BREZTRI and call your healthcare provider right away
    • Serious allergic reactions. Call your healthcare provider or get emergency medical care if you get any of the following symptoms: rash; hives; swelling of your face, mouth, and tongue; or breathing problems
    • Effects on your heart such as increased blood pressure, a fast or irregular heartbeat, or chest pain
    • Effects on your nervous system such as tremor or nervousness
    • Bone thinning or weakness (osteoporosis)
    • Acute narrow-angle glaucoma and cataracts. If you have new or worsening eye or vision problems, call your healthcare provider right away before taking another dose
    • Urinary retention. If you have new or worsening symptoms or difficulty urinating, stop taking BREZTRI and call your healthcare provider right away before taking another dose
    • Changes in laboratory blood values, including high levels of blood sugar (hyperglycemia) and low levels of potassium (hypokalemia). Low levels of potassium may cause symptoms of muscle spasm, muscle weakness, or abnormal heart rhythm
  • Most common side effects include: upper respiratory tract infection, pneumonia, hoarseness, back pain, thrush in your mouth and throat, flu, muscle spasms, urinary tract infection, cough, inflammation of the sinuses, and diarrhea

APPROVED USE

BREZTRI AEROSPHERE is a medicine used long term to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups.

BREZTRI is not used to relieve sudden breathing problems and will not replace a rescue inhaler. BREZTRI is not for the treatment of asthma.

Please see full Prescribing Information and Patient Information, and discuss with your doctor.

You may report side effects related to AstraZeneca products by clicking here.

isi-anchor

IMPORTANT SAFETY INFORMATION

  • BREZTRI combines 3 medicines, an inhaled corticosteroid (ICS) medicine (budesonide), an anticholinergic medicine (glycopyrrolate), and a long-acting beta2-adrenergic agonist (LABA) medicine (formoterol fumarate). LABA medicines, such as formoterol fumarate, when used alone can increase the risk of hospitalizations and death from asthma problems. When an ICS and LABA are used together, this risk is not significantly increased
  • Do not use BREZTRI if you are allergic to budesonide, glycopyrrolate, formoterol fumarate, or any of the ingredients in BREZTRI
  • Do not take BREZTRI with other medicines that contain a long-acting beta2-adrenergic agonist (LABA) or an anticholinergic for any reason. Tell your healthcare provider about all your medical conditions and about all the medicines you take
  • BREZTRI should be taken as 2 puffs, 2 times each day. Do not use BREZTRI more often than prescribed
  • Call your healthcare provider or get medical care right away if your breathing problems get worse, if you need to use your rescue inhaler more often than usual, or your rescue inhaler does not work as well to relieve your symptoms
  • BREZTRI can cause serious side effects, including:
    • Fungal infection in your mouth or throat (thrush). Rinse your mouth with water without swallowing after using BREZTRI to help reduce your chance of getting thrush
    • Pneumonia. People with COPD have a higher chance of getting pneumonia. Call your healthcare provider if you notice an increase in mucus (sputum) production or change in mucus color, fever, chills, increased cough, or increased breathing problems
    • Weakened immune system and increased chance of getting infections (immunosuppression)
    • Reduced adrenal function (adrenal insufficiency). This can happen when you stop taking oral corticosteroid medicines and start inhaled corticosteroid medicine
    • Sudden breathing problems immediately after inhaling BREZTRI. If this happens, stop taking BREZTRI and call your healthcare provider right away
    • Serious allergic reactions. Call your healthcare provider or get emergency medical care if you get any of the following symptoms: rash; hives; swelling of your face, mouth, and tongue; or breathing problems
    • Effects on your heart such as increased blood pressure, a fast or irregular heartbeat, or chest pain
    • Effects on your nervous system such as tremor or nervousness
    • Bone thinning or weakness (osteoporosis)
    • Acute narrow-angle glaucoma and cataracts. If you have new or worsening eye or vision problems, call your healthcare provider right away before taking another dose
    • Urinary retention. If you have new or worsening symptoms or difficulty urinating, stop taking BREZTRI and call your healthcare provider right away before taking another dose
    • Changes in laboratory blood values, including high levels of blood sugar (hyperglycemia) and low levels of potassium (hypokalemia). Low levels of potassium may cause symptoms of muscle spasm, muscle weakness, or abnormal heart rhythm
  • Most common side effects include: upper respiratory tract infection, pneumonia, hoarseness, back pain, thrush in your mouth and throat, flu, muscle spasms, urinary tract infection, cough, inflammation of the sinuses, and diarrhea

APPROVED USE

BREZTRI AEROSPHERE is a medicine used long term to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups.

BREZTRI is not used to relieve sudden breathing problems and will not replace a rescue inhaler. BREZTRI is not for the treatment of asthma.

Please see full Prescribing Information and Patient Information, and discuss with your doctor.

You may report side effects related to AstraZeneca products by clicking here.

Read More